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Rachel Knuth

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Rachel Knuth is a junior Biology major who aspires to be a doctor. She is a member of the Honors program, the Biology Club, and the Health Profession’s Organization.

Rachel is interested in spinal cord regeneration in the goldfish, and conducts her research in the laboratory of Dr. Robert Waldeck.  Spinal cord injury resulting from trauma is extremely difficult to heal; thus it often leads to paralysis.  This is due to the fact that when nerve cells are damaged and their connections are severed, they have a difficult time regrowing and re-establishing these connections.  However, animals such as goldfish routinely regenerate their spinal cords following injury.  If she can learn how these animals regrow their spinal cord nerves, she could help identify potential avenues for spinal injury treatment in humans. She actively researched the topic, wrote a research proposal, entitled "Determining the presence of laminin as a growth promoting molecule in goldfish spinal cord regeneration", and was awarded the President’s Summer Research Fellowship in 2011.

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    She selected her research based both on her personal interests and by observing Dr. Waldeck in his lab.  "It is really a good idea to start early, preferably in your freshman year", Rachel says.  Rachel also advises other students, "Pick a research topic that really excites you."  Rachel hopes to continue this research through her senior year as she completes her Honors thesis.  She also hopes to make important contributions to the field of spinal injury rehabilitation.  This experience will clearly help her in her future studies as a doctor.
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Regenerating neurons in the goldfish spinal cord, stained with HRP
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